WHO expects that more cases in non-endemic areas will be reported. endobj Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. Based on currently available information, cases have mainly but not exclusively been identified amongst men who have sex with men (MSM) seeking care in primary care and sexual health clinics. Cases of monkeypox in non-endemic countries reported to WHO between 13 to 21 May 2022 as at 13:00. It is not necessary to obtain negative laboratory results for listed common causes of rash illness in order to classify a case as suspected. It may, however, be prudent to exclude pre-school children from daycare, nursery, or other group settings. Probable and confirmed cases should be reported immediately to WHO through IHR National Focal Points (NFPs) under the International Health Regulations (IHR 2005). She advised anyone who is having changes in sex partners regularly, or having close contact with individuals that they dont know, to come forward if they develop a rash. So far, there have been no deaths associated with this outbreak. He told Sky News: "As with any new disease, and obviously after the Covid pandemic doubly so, we continue to monitor this very closely. As of 21 May, 13:00, 92 laboratory confirmed cases, and 28 suspected cases of monkeypox with investigations ongoing, have been reported to WHO from 12 Member States that are not endemic for monkeypox virus, across three WHO regions (Table 1, Figure 1). Avoid sharing utensils or cups. The minimum data to be captured are included above under Reporting. Recommended personal protective equipment (PPE) includes gloves, gown, medical mask and eye protection goggles or face shield. If the contact develops a rash, they need to be isolated and evaluated as a suspected case, and a specimen should be collected for laboratory analysis to test for monkeypox. Options for monitoring by public health authorities are dependent on available resources. WHO is convening experts to discuss recommendations on vaccination. This includes no travel, providing details for contact tracing and avoiding direct contact with immunosuppressed people, pregnant women and children under 12. The situation is evolving and WHO expects there will be more cases of monkeypox identified as surveillance expands in non-endemic countries. Geographical distribution of confirmed and suspected cases of monkeypox in non-endemic between 13 to 21 May 2022, as at 13:00. Considerations related to risk communication and community engagement. These considerations may change as we learn more from the 2022 global outbreak of monkeypox. OpenWHO. Available at: https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385. This includes providing public health advice through the channels that target audiences use on how the disease transmits, its symptoms, preventive measures and what to do in case of suspect or confirmed infection. Those receiving the vaccines are at high risk of developing symptoms. UKHSA also advises that they are offered a smallpox vaccine. Health workers caring for patients with suspected or confirmed monkeypox should implement standard, contact and droplet precautions. Asymptomatic contacts can continue routine daily activities such as going to work and attending school (i.e., no quarantine is necessary), but should remain close to home for the duration of surveillance. Exposure investigation should cover the period between five and 21 days prior to symptom onset. Online training module. Theres a New Centrist Political Party. A contact is defined as a person who, in the period beginning with the onset of the source cases first symptoms, and ending when all scabs have fallen off, has had one or more of the following exposures with a probable or confirmed case of monkeypox: Cases can be prompted to identify contacts across a number of contexts, including household, workplace, school/nursery, sexual contacts, healthcare, houses of worship, transportation, sports, social gatherings, and any other recalled interactions. Prior to reporting for work each day, the health worker should be interviewed regarding evidence of any relevant signs/symptoms as above. The identification of confirmed and suspected cases of monkeypox without any travel history to an endemic area in multiple countries is atypical, hence, there is an urgent need to raise awareness about monkeypox and undertake comprehensive case finding and isolation (provided with supportive care), contact tracing and supportive care to limit further onward transmission.

Figure 1. Its Going Nowhere. %PDF-1.7 Wash hands often with soap and water or use an alcohol-based hand sanitizer, especially after direct contact with the rash. Historically, vaccination against smallpox had been shown to be protective against monkeypox. Laboratory confirmation of suspect cases is important but should not delay implementation of public health actions. The sudden cancellation of Ant Groups IPO shocked investors, but Beijing's slapdown of Jack Ma was years in the making. 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Increasing awareness among potentially affected communities, as well as health care providers and laboratory workers, is essential for identifying and preventing further secondary cases and effective management of the current outbreak. aspiration or open suctioning of respiratory tract specimens, bronchoscopy, intubation, cardiopulmonary resuscitation), be required for any reason and cannot be delayed, then as a matter of standard practice, a respirator (FFP2 or EN certified equivalent or US NIOSH-certified N95) must be used by health care workers instead of a medical mask. Genome sequence from a swab sample from a confirmed case in Portugal, indicated a close match of the monkeypox virus causing the current outbreak, to exported cases from Nigeria to the United Kingdom, Israel and Singapore in 2018 and 2019. Do not share items that have been worn or handled with other people or animals. Direct monitoring is a variation of active monitoring that involves at least daily either physically visiting or visually examining via video for signs of illness. Congregate care settings, such as correctional facilities and homeless shelters, should follow CDCsPreventing Monkeypox Spread in Congregate Settings. Some countries may hold smallpox vaccine products which could be considered for use according to national guidance. National and international regulations on transport of infectious substances should be strictly followed during the sample packing and transportation to the testing laboratories. One or more of the following signs or symptoms, since 15 March 2022: for which the following common causes of acute rash do not explain the clinical picture: varicella zoster, herpes zoster, measles, Zika, dengue, chikungunya, herpes simplex, bacterial skin infections, disseminated gonococcus infection, primary or secondary syphilis, chancroid, lymphogranuloma venereum, granuloma inguinale, molluscum contagiosum, allergic reaction (e.g., to plants); and any other locally relevant common causes of papular or vesicular rash. This includes avoiding close or physical contact with other. Considerations related to clinical management and infection prevention and control in health care settings. CDC and Health Partners Responding to Monkeypox Case in the U.S. 18 May 2022, Ministry of Health Portugal Press Release, 18 May 2022, First draft genome sequence of Monkeypox virus associated with the suspected multi-country outbreak, May 2022 (confirmed case in Portugal), https://doi.org/10.1371/journal.pntd.0010141, https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385, Multi-country monkeypox outbreak in non-endemic countries, Genomic sequencing, where available, have been undertaken to determine the monkeypox virus clade(s) in this outbreak. The first human case was identified in a child in the Democratic Republic of the Congo in 1970. Table 1. There is little immunity to monkeypox among younger people living in non-endemic countries since the virus has not been present there. Until all signs and symptoms of monkeypox illness have fully resolved. Additionally, a bandage, sheet or gown can be used to cover lesions in order to minimize potential contact with lesions. The patient should also be instructed to wear a medical mask when they come into close contact (under 1m) with health workers or other patients, if they can tolerate it. And Alibaba and Ant aren't the only tech firms under scrutiny by Chinese regulators. Cohort (confirmed with confirmed, suspected with suspected) can be implemented if single rooms are not available, ensuring minimum of 1-meter distance between patients. Various animal species have been identified as susceptible to the monkeypox virus. Retrospective cases cannot be laboratory confirmed; however, serum from retrospective cases can be collected and tested for anti-orthopoxvirus antibodies to aid in their case classification. Countries may want to consider timely vaccination of close contacts as post-exposure prophylaxis or for certain groups of health care workers for pre-exposure vaccination. Active monitoring is when public health officials are responsible for checking at least once a day to see if a person under monitoring has self-reported signs/symptoms. To date, all cases whose samples were confirmed by PCR have been identified as being infected with the West African clade. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. !acgUU YAztd?/byCz5I-o}Z.tur8cpB0"-X2_IJ[<<8$>rzx `5gpG~ 'Ensx5~OQMf,Yxzt^lQpW^sO,Q(Y.=vx0 i2D4$ O)Kv8~Cxa|[x:z[x\(W[Pt?~$]~GnhimD!ap`(}rWt_?0:0~l]/dW&}duP%Y OPCYmrNAp'XR5D2B6r=tJAEVd#Q{CDQG;;g%dnd7I!CJ*0RAu>}=+>g&9)a#Oe!Y#d4mRN has an epidemiological link (face-to-face exposure, including health workers without eye and respiratory protection); direct physical contact with skin or skin lesions, including sexual contact; or contact with contaminated materials such as clothing, bedding or utensils to a probable or confirmed case of monkeypox in the 21 days before symptom onset, reported travel history to a monkeypox endemic country, has had multiple or anonymous sexual partners in the 21 days before symptom onset, face-to-face exposure (including health care workers without appropriate PPE), direct physical contact, including sexual contact, contact with contaminated materials such as clothing or bedding. A suspected or probable case for which laboratory testing by PCR and/or sequencing is negative for monkeypox virus. Direct skin-to-skin contact, including sexual and/or close intimate contact, has been identified as a predominant type of exposure for persons with monkeypox in the United States. PPE should be disposed of prior to leaving the isolation area where the patient is admitted. can be further used to identify contacts. Boy Scouts Must Change $2.7 Billion Sex Abuse Fund, Judge Rules, Gazprom Sets Out Challenges for Resuming Normal Nord Stream Flow, Musk Files Defense Under Seal as Twitter Trial Set for Oct. 17, Alibaba Added to SEC List of Chinese Firms Facing Delisting, Permira Is in Lead to Buy Reorg Research From Warburg Pincus, House Passes Assault Weapons Ban, Faces Little Chance in Senate, Japans Youth Shun Politics, Leaving Power With the Elderly, Calstrs Posts 1.3% Loss for Latest Fiscal Year After Market Rout, Most Expensive Condo in Los Angeles Hits Market at $75 Million, Review: Beyonc Escapes to Dance World in "Renaissance", Neil Patrick Harris Is Suddenly Single in Comedy 'Uncoupled', The FourMysteries of Pelosis Troublesome Taiwan Trip, Manufacturers That Sell to Consumers Feel the Pinch. The guidance comes after Dr Susan Hopkins, chief medical adviser for UKHSA, warned that monkeypox is spreading through community transmission. These precautions are applicable in any health facility including outpatient services and hospitals. Eating inadequately cooked meat and other animal products of infected animals is a possible risk factor. Avoid close physical contact, including sexual and/or close intimate contact, with other people.

The situation is evolving and WHO expects there will be more cases of monkeypox identified as surveillance expands in non-endemic countries. stream xkOH;?+bj0e9.I~0! Healthcare workers who have cared for or otherwise been in direct or indirect contact with monkeypox patients while adhering to recommended IPC measures may undergo self-monitoring or active monitoring as determined by local public health authorities. Retrospective cases found by active search may no longer have the clinical symptoms of monkeypox (they have recovered from acute illness) but may exhibit scarring and other sequelae.

Monitoring exposed health workers and caregivers. OpenWHO. Countries currently reporting cases of the West African clade are Cameroon and Nigeria. A systematic review.

Signs/symptoms of concern include headache, fever, chills, sore throat, malaise, fatigue, rash, and lymphadenopathy. A pox-like disease in cynomolgus monkeys. Countries should be on the alert for signals related to patients presenting with unusual rash, vesicular or pustular lesions or lymphadenopathy, often associated with fever, in a range of community and health care settings, including but not limited to primary care, fever clinics, sexual health services, infectious disease units, obstetrics and gynecology, and dermatology clinics. So far the agency has confirmed 20 cases in the UK. The UK Health Security Agency (UKHSA) guidance now recommends that people who have had unprotected direct contact or high-risk environmental contact should isolate for three weeks. There is a high likelihood of identification of further cases with unidentified chains of transmission, including in other population groups. Careful planning is required to consider national laboratory testing capacity. Dr Hopkins said updated figures for the weekend will be given on Monday as she warned of more cases on a daily basis.

While a rash persists but in the absence of a fever or respiratory symptoms. "That being the case, the risk of community transmission is much lower, we have a working vaccine, if people present with symptoms or have very close contact, then we are advising that they quarantine for three weeks but the threshold for that is quite high - it really does have to be close physical or sexual contact. However, the extent of local transmission is unclear at this stage, as surveillance has been limited. Bloomberg Business of Sports lets you follow the money in the world of sports, reporting on trades, salaries, endorsements, contracts and collective bargaining. Whether people with immunosuppression have more. In his first public comments on the disease, Mr Biden added: It is a concern in that if it were to spread it would be consequential..

<> Cases of monkeypox in endemic countries between 15 December 2021 to 1 May 2022. Public health officials should work with travel operators and public health counterparts in other locations to assess potential risks and to contact passengers and others who may have had contact with an infectious patient while in transit. While the exact mechanisms of transmission of the present monkeypox outbreak are still being investigated, and they likely differ from those of SARS-CoV-2, it is important to remind that the general precautionary measures recommended against COVID-19 are also expected to largely protect from monkeypox virus transmission. CDC twenty four seven. The key objectives of surveillance and case investigation for monkeypox in the current context are to rapidly identify cases, clusters, and the sources of infection as soon as possible in order to provide optimal clinical care, isolate cases to prevent further transmission, identify and manage contacts and tailor effective control and prevention methods based on most commonly identified routes of transmission. Disease Outbreak News; Multi-country monkeypox outbreak in non-endemic countries. Attendance lists, passenger manifests, etc. Case reports should include at a minimum the following information: date of report; reporting location; name, age, sex and residence of the case; date of onset of first symptoms; recent travel history; recent exposure to a probable or confirmed case; relationship and nature of contact with probable or confirmed cases (where relevant); recent history of multiple or anonymous sexual partners; smallpox vaccination status; presence of rash; presence of other clinical signs or symptoms as per case definition; date of confirmation (where done); method of confirmation (where done); genomic characterization (if available); other relevant clinical or laboratory findings, particularly to exclude common causes of rash as per the case definition; whether hospitalized; date of hospitalization (where done); and outcome at time of reporting. 1959; 46:159. Any health worker or household member who has cared for a person with probable or confirmed monkeypox should be alert to the development of symptoms that could suggest monkeypox infection, especially within the 21-day period after the last date of care. Instead, healthcare providers should follow CDCs Infection Prevention and Control of Monkeypox in Healthcare Settings. Contacts should monitor their temperatures twice daily. Will Restaurant Week Be the Ticket? What is monkeypox and what are the symptoms? NYC Wants In-Person Dining Back. Contact tracing is a key public health measure to control the spread of infectious disease pathogens such as monkeypox virus. WHO is closely monitoring the current monkeypox outbreak.

Independent Oversight and Advisory Committee, The UK Health Security Agency News story on 16 May 2022, Monkeypox cases confirmed in England latest updates, WHO disease outbreak news, monkeypox, United Kingdom of Great Britain and Northern Ireland, 16 May 2022, WHO disease outbreak news, monkeypox, United Kingdom of Great Britain and Northern Ireland, 8 July 2021, WHO disease outbreak news, monkeypox, all items, Weekly epidemiological record (WER) no.11, 16 March 2018, Emergence of monkeypox in West Africa and Central Africa 1970-2017, Nigeria Centre for Disease Control. 2 0 obj Benin and South Sudan have documented importations in the past.

Concerns have been raised by the media with regard to the amplification of the spread of monkeypox virus in the context of large gatherings. Table 2. Items should be cleaned and disinfected before use by others. No associated deaths have been reported to date. Based on currently available information, cases have mainly but not exclusively been identified amongst men who have sex with men (MSM) seeking care in primary care and sexual health clinics. If monkeypox is suspected, the investigation should consist of (i) clinical examination of the patient using appropriate infection prevention and control (IPC) measures, (ii) questioning the patient about possible sources of infection and the presence of similar disease in the patients community and contacts, and (iii) safe collection and dispatch of specimens for monkeypox laboratory examination. A Legal Showdown Over Section 8 Discrimination Is Brewing in Dallas Suburb, FDICs Message to Crypto Investors: Digital Assets Arent Insured, Troubled Crypto Lender Babel Lost Big While Trading Client Funds, Ex-Voyager Executive Explores Competing Restructuring Plan for Crypto Lender. There is a vaccine recently approved for monkeypox which is not yet widely available. 3 0 obj Monkeypox, Monkeypox in the United States of America, WHO AFRO Weekly Bulletin on Outbreaks and Other Emergencies, Public Health Agency of Canada confirms 2 cases of monkeypox, US CDC media statement. More monkeypox cases being confirmed 'on a daily basis' in the UK. Climate change is increasingly threatening cities with catastrophic flooding. <> endobj There are two clades of monkeypox virus: the West African clade and the Congo Basin (Central African) clade. A person meeting the case definition for a suspected case. It allows for the interruption of transmission and can also help people at a higher risk of developing severe disease to more quickly identify their exposure, so that their health status can be monitored, and they can seek medical care faster if they become symptomatic. Standard precautions include strict adherence to hand hygiene, appropriate handling of contaminated medical equipment, laundry, waste and cleaning and disinfection of environmental surfaces. ", Mr Clarke said he was not aware of reports of a baby being in intensive care with monkeypox, adding: "What I would say is we are cautious but we are certainly not in a position where I would in anyway worry the public that this is some repeat of Covid, because it certainly does not appear to be anywhere near the same platform of seriousness.". Since 13 May 2022, cases of monkeypox have been reported to WHO from 12 Member States that are not endemic for monkeypox virus, across three WHO regions. The show takes listeners inside the business end of the sports world, and explains what it means to fans and their pocketbooks. As of July 15, 2022, transmission during brief interactions (such as a brief conversation), between people in close proximity and for a long duration (such as passengers seated near a person with monkeypox on an airplane), or during healthcare encounters, has not been reported for any person with monkeypox. Based on currently available information, cases have mainly but not exclusively been identified amongst men who have sex with men (MSM) seeking care in primary care and sexual health clinics. [2] Monkeypox endemic countries are: Benin, Cameroon, the Central African Republic, the Democratic Republic of the Congo, Gabon, Ghana (identified in animals only), Cte dIvoire, Liberia, Nigeria, the Republic of the Congo, and Sierra Leone. Many are now looking to Rotterdam, and its long history of innovation when it comes to holding water at bay. N.B. A case meeting the definition of either a suspected or probable case and is laboratory confirmed for monkeypox virus by detection of unique sequences of viral DNA either by real-time polymerase chain reaction (PCR) and/or sequencing. % The disease, first found in monkeys, can be transmitted from person to person through close physical contact, including sexual intercourse, and is caused by the monkeypox virus. Endemic monkeypox disease is normally geographically limited to West and Central Africa.

The UK Health Security Agency (UKHSA) guidance now recommends that people who have had "unprotected direct contact or high-risk environmental contact" should isolate for three weeks. However, if a person with monkeypox is unable to remain fully isolated throughout the illness, they should do the following: These recommendations do not apply in healthcare settings, such as hospitals and outpatient clinics. Immediate actions focus on informing those most at risk for monkeypox infection with accurate information, stopping further spread and protecting frontline workers. In passive monitoring, identified contacts are provided with information on the signs/symptoms to monitor, permitted activities, and how to contact the public health department if signs/symptoms develop. Isolation and transmission-based precautions should be continued until resolution of symptoms (including the resolution of any rash and scabs that have fallen off and healed). A global case reporting form is under development. Although there is no direct vaccine for monkeypox, a form of smallpox vaccine has been used in those who are contacts of cases. While one vaccine (MVA-BN) and one specific treatment (tecovirimat) were approved for monkeypox, in 2019 and 2022 respectively, these countermeasures are not yet widely available. Because of the public health risks associated with a single case of monkeypox, clinicians should report suspected cases immediately to national or local public health authorities regardless of whether they are also exploring other potential diagnoses.

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